Components of marijuana show “consistent and statistically significant anti-tumor effects” in certain types of cancer, including glioblastoma and breast cancer, according to a new scientific review that also found cannabinoids seem to “enhance chemotherapy efficacy.”
The research, published in the journal Pharmaceuticals, involved a systematic meta-analysis of preclinical trial data investigating the relationship between cannabinoid therapies and multiple cancer types.
Researchers at Semmelweis University and the University of Pécs said their work “provides the most comprehensive systematic synthesis to date of preclinical evidence regarding the antitumor effects of cannabinoids across a wide spectrum of cancer models.”
The review determined that cannabis compounds “show promise as adjuncts in oncotherapy, particularly in glioblastoma and breast cancer, to enhance chemotherapy efficacy.”
“Cannabinoids demonstrated consistent and statistically significant antitumor effects in glioblastoma and breast cancer models,” the study authors said, noting that there’s “additional supportive evidence in lung and prostate cancer.”
“Glioblastoma emerged as the tumor type with the most reproducible evidence base,” the study said.
“Cannabinoids show emerging potential as adjuncts in oncological treatment, with relatively consistent signals observed particularly in glioblastoma and breast cancer models.”
Of the cannabinoids included in the analysis, non-intoxicating CBD “demonstrated the broadest and most favorable profile, with
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