Cannabis and its components appear to play a role in alleviating the symptoms of restless leg syndrome (RLS), according to a new scientific review.
RLS is a neurological disorder that involves an urge to move the legs and that sometimes involves sensations like tingling or aching.
“Cannabinoids—particularly CBD—may hold therapeutic promise in RLS through multi-system neurobiological effects,” the study, published in the Annals of Indian Academy of Neurology, said.
Researchers at the All India Institute of Medical Sciences conducted a comprehensive search of previously published studies on the issue, ultimately deciding to include seven papers in their review.
Current evidence indicates that cannabis, in various forms, may alleviate or prevent symptoms of RLS through multiple mechanisms,” they concluded, though they also cautioned that studies published to date are “limited to case reports, cross-sectional surveys, and post hoc analyses.”
High-quality randomized controlled trials will be needed to support more sweeping conclusions and recommendations about the use of medical marijuana to treat RLS, they said.
“The evidence suggests that cannabis or cannabidiol may improve or prevent RLS symptoms.”
That said, the scientific review includes a number of existing studies that provide initial evidence for cannabinoids’ efficacy in addressing RLS.
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