Cannabidiol (CBD), a non-intoxicating compound in marijuana, “holds substantial promise as an anti-tumor agent” in addition to its other anti-inflammatory properties, a new scientific review
Scientists explored CBD’s effect on many types of cancer—including some of the most aggressive ones, such as glioblastoma, which affects the brain. They also noted it can help suppressing the growth and metastasis of other cancers, including breast, lung, colorectal, ovarian and prostate, among others.
“CBD exhibits multi-targeted anti-tumor effects by disrupting key cancer hallmarks,” they found.
The paper, funded by National Natural Science Fund of China, was designed as a systematic review of previous studies evaluating the cancer fighting qualities of CBD.
The idea behind much of the research is to study how cancer cells survive by hijacking normal biological signals like growth cues, stress responses and immune pathways. The novelty scientists found was that CBD doesn’t seem to target just one of these systems and instead nudges several of them at once, pushing cancer cells toward collapse through overlapping and complementary effects.
In colon cancer models, for example, CBD interferes with a receptor called GPR55, which helps tumors grow and migrate. Blocking that receptor weakens a pathway cancer cells rely on to divide
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