Marijuana can have a number of effects on people who use it but there are no known instances of someone fatally overdosing from consuming cannabis, federal officials say.
“No deaths from overdose of marijuana have been reported,” the Drug Enforcement Administration (DEA) said in a new update to its “Drugs of Abuse” publication for 2026.
That said, the agency is cautioning that cannabis’s effects on perception and coordination can cause “serious impairments in learning, associative processes, and psychomotor behavior (driving abilities)” and that long-term use can lead to “physical dependence and withdrawal following discontinuation, as well as psychological addiction or dependence.”
The report also notes that “there have been an increasing number of emergency room visits involving marijuana edibles.”
On the other hand, however, DEA notes that marijuana use can lead to “merriment, happiness, and even exhilaration at high doses.”
While the updated 119-page report’s marijuana section is largely the same as the one in the previous edition published in 2024, it has been revised to note the Trump administration’s move to federally reschedule cannabis as well as to more favorably characterize the growing number of states that are changing their own laws.
“Over the last three decades, the majority
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